This is the second part of an integrated review of disseminated gonococcal infection (DGI) and gonococcal arthritis (GCA). A54.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Conjunctival gonococcal infection can result in scarring, permanent visual impairment and blindness. GONOCOCCAL infections are prevalent all over the world, in particular youth, with disseminated complications. These results do not support the hypothesis that circulating immune complexes are involved in the pathogenesis of disseminated gonococcal arthritis‐dermatitis syndrome. The outcome is potentially fatal. Neisseria gonorrhoeae causes disseminated gonococcal infection (DGI), the most common form of infectious arthritis seen in both community and major teaching hospitals. Disseminated gonococcemia, acral pustules. 2012 European guideline on the diagnosis and treatment of gonorrhoea in adults. Abstract published at Hospital Medicine 2016, March 6-9, San Diego, Calif.. Abstract 778 Journal of Hospital Medicine, Volume 11, Suppl 1. Disseminated gonococcal infection. Synovial fluid cultures are positive for N gonorrhoeae in no more than 50% of cases [ 1 ] and alone are insufficient to establish the diagnosis. When the bacteria spread, disseminated gonorrhea can cause symptoms like fevers, chills, and a … Author information: (1)University of Texas Southwestern Medical Center, Dallas, TX melissa.mauskar@utsouthwestern.edu. Genital and extragenital lesions can mimic the skin lesions that occur in disseminated gonococcal infection; Viral culture, polymerase chain reaction (PCR), and direct fluorescence antibody confirm the presence of the causative agent. gonorrhoeae stimulates the production of antibodies to many common, species- specific, and type-specific antigens. Examination of the eyes with a slit lamp is recommended so that infection of the cornea can be excluded. Characteristic findings on physical examination There are two recognizable syndromes that may overlap. However, gonococcal antigen was not found in either serum or synovial fluid. Disseminated infection is one of the major threats of gonococcal infection. The L-antigen is an envelop antigen and antibodies to it could be demonstrated by various methods in more than 90% of the patients after the first Alternative Names Disseminated gonococcal infection ,DGI, Disseminated gonococcemia Florez-Pollack S(1), Mauskar MM(1). Disseminated Gonococcal Infection. This is the American ICD-10-CM version of A54.9 - other … Rates of gonococcal infection per 100,000 by state and outlying regions (2016). Am Fam Physician. [Medline] . Most patients are febrile and bacteremic. It covers clinical manifestations, spectrum of GCA, diagnosis and treatment. Courtesy of the Centers for Disease Control and Prevention (CDC). Disseminated Gonococcal Infection (DGI) This results from gonococcal bacteremia and only occurs in up to 3% of those with gonorrhea. Disseminated gonococcal infection may affect joints causing polyarthralgia and, potentially, septic arthritis. Disseminated gonococcal infection presents as a few skin lesions that are limited to the extremities. Non-disseminated gonococcal infection Empiric treatment for gonorrhea is usually initiated prior to receipt of laboratory results. Disseminated gonococcal infection can be confirmed by isolation of gonococci from potential sites, including urethra, cervix, rectum, oropharynx, and blood. However, a microbiologic diagnosis is important for further management in order to determine the need for test of cure, partner management, and for public health reasons. Definition: Gonococcal arthritis is inflammation of a joint due to a gonorrhea infection.. Gonococcal arthritis is a type of septic arthritis.This is inflammation of a joint due to a bacterial or fungal infection. Furthermore, cohort studies suggest an increased risk of HIV acquisition in the presence of gonorrhoea infection [24] . Suspected disseminated gonococcal infection (DGI) DGI occurs when infection with N gonorrhoeae is left untreated. Gonococcal conjunctivitis can present with a thick white/yellow discharge. Gonococcal antibody was detected in 47% of patients when they presented with the syndrome. Disseminated herpes simplex, the same virus that causes cold sores and genital herpes, can disseminate after the initial adult or neonatal infection. Diagnosis of Disseminated Gonococcal Infection Complicated by Acute Hepatitis B Infection. Are You Confident of the Diagnosis? Early diagnosis and adequate therapy are necessary to prevent serious complications.